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BACKGROUND Patients with ankylosing spondylitis(AS)combined with severe cervical fusion deformity have difficult airways......
Heart failure(HF)is a clinical syndrome that results from a structural or functional cardiac disorder that reduces the a......
Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular,car
Stroke is a common cause of death and disability.Allisartan isoproxil(ALL)is a new angiotensinⅡreceptor blocker and a n......
Objective:To investigate the pharmacological potential of Argemone mexicana in treating constipation and emesis by using......
2008393 Effects of angiotensin Ⅱ type 1 receptor blocker on triglyceride metabolism in the liver: experiment with Zucke......
Landiolol, an ultra-short-acting β1-blocker, is useful for managing supraventricular tachyarrhythmia
AIM: To investigate whether landiolol, an ultra-shortacting β1-antagonist, can safely and effectively control heart rat......
Angiotensin Ⅱ receptor blocker provides pancreatic β-cell protection independent of blood pressure l
Aim:Several epidemiological studies have suggested that treatment with angio-tensin Ⅱ type 1 receptor blocker provided......
Combined effects of ramipril and angiotensin Ⅱ receptor blocker TCV116 on rat congestive heart failu
Background Congestive heart failure (CHF) is a majorrrrrrrrnr cause of morbidity and mortality worldwide and angiotensin......
Observation of functional remodeling of Ca~(2+)-activated Cl~- channel in pacing-induced canine fail
Objective To study whether Ca2+-activated Cl-current (Ito2) contributes to the functional remodeling of the failing hear......
ZD 7288,an HCN channel blocker,attenuates chronic visceral pain in irritable bowel syndrome-like rat
AIM:To investigate the effects of ZD 7288,a hyperpolarization-activated cyclic nucleotide-gated(HCN)channel blocker,on r......
INTRODUCTION Hypertension,a presently rapidly expanding disease, has been becoming a major risk factor for cardiocerebro......
Inhibition of calcium channel blocker associated with lowering C-reactive protein level in rupture o
Background As to abdominal aortic aneurysm (AAA) disease, our major challenge faced in clinical practice is effective dr......
术语ｂｌｏｃｋｅｒ、ａｎｔａｇｏｎｉｓｔ和ｉｎｈｉｂｉｔｏｒ有区别吗？在生物医学期刊、专著和教材中，常见混用ｂｌｏｃｋｅｒ、ａｎｔａｇｏｎｉｓｔ和ｉｎｈｉｂｉｔｏｒ的情况。尽管三者在表达生理功能或药理作用的水平上相当近似，但严格区......
AIM:Myocardial fibrosis induced by activated cardiac fibroblasts(CFs)is thought to play a key role in the pathogenesis o......
通过一项多中心、前瞻性随机对照试验阐明以坎地沙坦为基础的治疗对高血压患者并发癌症以及癌症死亡的影响。该试验对比坎地沙坦为......
Central Nervous System Toxicity of Sodium Nitroprusside in Treatment of Patients with Aortic Dissect
This study examined the sodium nitroprusside (SNP) toxicity to central nervous system (CNS) in treatment of patients wit......
An organic light-emitting devices of highly efficient white phosphor using an electron/exciton block
Highly efficient white phosphorescent organic light-emitting devices (WOLEDs) was fabricated using an electron/exciton b......
Background Although mi RNAs have been shown to associate with a variety of diseases,whether mi RNAs in monocyte associat......
AIM To determine the prevalence of QT prolongation in a large series of end stage liver disease(ESLD) patients and its a......
目的综合评价利尿剂、β受体阻滞剂、血管紧张素转换酶抑制剂(ACEI)、血管紧张素Ⅱ受体阻滞剂(ARB)和钙通道阻滞剂(CCB)5类降压药......
The gap junction blocker carbenoxolone enhances propofol and sevoflurane-induced loss of consciousne
General anesthetics induce loss of consciousness by inhibiting ascending arousal pathways, and they interfere with gap j......
Based on the gate—related receptor hypothesis,a quantitative study on kinetics and state—dependency of metoclopramide......
A new hypothesis on mechanisms of action of the sodium channel blocker,the gate—related receptor hy-pothesis,has been ......
Ectopic discharges trigger sympathetic sprouting in rat dorsal root ganglia following peripheral ner
Experimental backgrounds of ectopic discharges were made by i.p. administrating of 4-aninopyriding (4-AP), a K+ channel ......
Renal artery stenosis (RAS) is a frequently overlooked clinical entity that can cause uncontrolled hypertension and lead......
Hyposmotic membrane stretch potentiated muscarinic receptor agonist-induced depolarization of membra
AIM:To investigate the relationship betweenhyposmotic membrane stretch and muscarinic receptoragonist-induced depolariz......
OBJECTIVE: To review the relationship between calcium ion channel and epilepsy for well investigating the pathogenesis o......
Objective Angiotensin Ⅱ(Ang Ⅱ)contributes to modulating blood pressure by stimulation of Ang Ⅱ AT1 receptors.We devis......
Effects of chronic peripheral pretreatment with an angiotensin II type-1 receptor blocker on apoptos
Chronic systemic treatment with blockers of angiotensin II type-1(AT1) receptors inhibits ischemia-induced apoptosis and......
Mitochondrial K+-ATP (mito-KATP) channels play an important role in cellular function and survival following ischemic st......
Benefit of combination β-blocker and endoscopic treatment to prevent variceal rebleeding: A meta-ana
AIM: To determine whether the association of β-blockers with endoscopic treatment is superior to endoscopic treatment a......
Accumulating evidence has suggested that the gap junction plays an important role in the determination of cerebral ische......
Changes in ectopic discharges from axons in an injured nerve were examined while agents that interact with ion channels ......
Inhibitory Effect of Anisodamine on the Neuropathic Hyperalgesia Following Peripheral Nerve Injury(Ⅱ
A peripheral neuropathy with hyperalgesia and allodynia was produced by loosely tying constrictive ligature around the l......
Angiotensin II receptor blocker as a novel therapy in acute lung injury induced by avian influenza A
Dear Editor,Since the first recognized case of human infection with avian influenza H5N1 virus in 1997,the worldwide spr......
Objective To compare cost-effectiveness between endoscopical esophageal variceal ligation(EVL)combined non-selective bet......
Usefulness of vonoprazan,a potassium ion-competitive acid blocker,for primary eradication of Helicob
AIM To investigate usefulness of triple therapy with vonoprazan,a potassium ion-competitive acid blocker and antibiotics......
Effect of muscarinic blocker on enhancing action of fructus aurantilii immaturus in the intestinal m
Ｓｕｂｊｅｃｔｈｅａｄｉｎｇｓｆｕｒｃｔｕｓａｕｒａｎｔｉｉｍｍａｔｕｒｕｓ；ｓｍａｌｉｎｔｅｓｔｉｎｅ；ａｔｒｏｐｉｎｅ；ｅｌｅｃｔｒｏｐｈｙｓｉｏｌｏｇｙＡｂｓｔｒａｃｔＡＩＭＴｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｅｃｔｏｆＦｒｕｃｔｕｓＡｕｒａｎ...
Subjectheadingsfurctusaurantiimmaturus; smalintestine; atropine; electrophysiologyAbstractAIMToinvestigatetheefecto......
EXPERIMENT STUDY ON THE EFFECT OF SHENG-MAI INJECTION ON THE CONTRACTIVITY OF DIAPHRAGM AND ITS MECH
In this study the effect of Sheng-ai Injection i.e. Red Ginseng-Ophiopogon Root Injection (one kind of traditional Chin......
AIM:Toosendanin is a pre-synaptic blocker at theneuromuscular junction and its inhibitory effect is dividedinto an init......
INVOLVEMENT OF NITRIC OXIDE IN THE VASODILATOR AND DEPRESSOR EFFECT OF CALCITONIN GENE-RELATED PEPTI
In present study,we examined the effects of N~G-nitro-L-arginine(LNNA),an inhibitor of nitric oxide synthase(NOS),and/or......
AIM: To study the serum level of flunarizine, a Ca~(2+) channel blocker, we established a sensitive, accurate and effic......
目的:研究尼群地平(Nit)对自发性高血压大鼠红细胞膜钙结合力和红细胞内总钙含量的作用。方法:应用尾套法测清醒大鼠收缩压,按改良......
Interaction between CI~- channels and CRAC-related Ca~(2+)signaling during T lymphocyte activation a
Aim:To test the hypothesis that Cl~- channel blockers affect T cell proliferationthrough Ca~(2+)-release-activated Ca~(......
Aim:To determine the Ca~(2+)source and cellular mechanisms of spontaneous Ca~(2+)oscillations in hippocampal astrocytes......
Effects of short-acting β-adrenergic blocker on B-type natriuretic peptide at early stage of postres
Postresuscitation myocardial dysfunction is reversible heart failure and B-type natriuretic peptide (BNP) is a biochemic......
Effects of angiotensin converting enzyme inhibitor,angio-tensin II type I receptor blocker and their
Background Transforming growth factor (TGF) β1-Smads signal plays an important role in cardiac remodeling following myo......
